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MEASUREMENT OF CIRCULATING MUTATION BURDEN

RECRUITINGSponsored by Centre Francois Baclesse
Actively Recruiting
SponsorCentre Francois Baclesse
Started2025-07-04
Est. completion2027-07-15
Eligibility
Age30 Years – 50 Years
SexFEMALE
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06792721

Summary

Cancer-free women with a hereditary predisposition to breast and/or ovarian cancer

Eligibility

Age: 30 Years – 50 YearsSex: FEMALEHealthy volunteers accepted
Inclusion Criteria:

* Female participant
* Participant undergoing oncogenetic follow-up at the Centre François Baclesse
* Participant belonging to a pair of related biological siblings
* Within the sibling pair, one participant is a carrier of a hereditary predisposition linked to a BRCA1/2 mutation (case), and the other participant is not a carrier (control).
* Participant between 30 and 50 years of age
* Participant affiliated to a social security scheme
* Participant having given her consent to participate by signing an informed consent form prior to any specific study-related procedure.

Exclusion Criteria:

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Conditions7

BRCA MutationBreast CancerBreast CarcinomaCancerGenetic Predisposition to CancerMutation BurdencfMB

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