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Orexin Gene in Anorexia Nervosa

RECRUITINGSponsored by Istituto Auxologico Italiano
Actively Recruiting
SponsorIstituto Auxologico Italiano
Started2024-06-19
Est. completion2026-06-30
Eligibility
Age18 Years+
SexFEMALE
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06800898

Summary

The objectives of this study will be to determine the methylation of the promoter of the Orexin A (OX-A) and B (OX-B) genes in young women (\> 18 years) with Anorexia Nervosa (AN), compared with a control group; and to evaluate the relationship of promoter methylation of the genes for OX-A and OX-B with the severity of the eating disorder, psychiatric comorbidities (in particular, depression), and sleep quality.

Eligibility

Age: 18 Years+Sex: FEMALEHealthy volunteers accepted
Patients with Anorexia Nervosa:

Inclusion Criteria:

* Female sex
* Age 18 years and older
* Anorexia Nervosa
* Hospitalized at the Division of Eating and Nutrition Disorders, Istituto Auxologico Italiano, IRCCS, Piancavallo, Italy

Exclusion Criteria:

* Absence of signed informed consent

Control group:

Inclusion Criteria:

* Female sex
* Age 18 years and older
* Body Mass Index between 18.5 and 24.9 kg/m2

Exclusion Criteria:

* Absence of signed informed consent
* Presence of any physical and mental pathology

Conditions2

Anorexia NervosaDepression

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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