Effects of Circadian Rhythm on Glycemic Regulation During Continuous Moderate Exercise and Intense Intermittent Disease in Adolescents Living With Type 1 Diabetes

Summary

Interventional research with minimal risks and constraints on the effects of circadian rhythm on glycemic regulation during intense moderate, continuous and intermittent exercise in adolescents living with type 1 diabetes

Eligibility

Inclusion Criteria:

* Children and adolescents aged 10 to 16;
* Living with type 1 diabetes for at least 1 year with HbA1c less than or equal to 12%;
* Socially insured ;
* Having given their written consent to participate in the research, as well as that of their legal guardians;
* Willing to comply with all research procedures and duration.

Exclusion Criteria:

* Clinically significant microvascular complications: nephropathy (estimated glomerular filtration rate less than 40 ml/min), neuropathy or severe proliferative retinopathy as assessed by the investigator;
* Recent acute macrovascular event (\< 3 months), e.g. acute coronary syndrome or cardiac surgery;
* Abnormal blood picture and/or anemia;
* Current pregnancy;
* Other serious medical condition likely to interfere with study participation or ability to complete exercise periods in the judgment of the investigator (e.g., orthopedic limitation);
* Inability to receive informed information;
* Inability to participate in the entire study;
* Lack of social security coverage;
* Refusal to sign the consent form.

Conditions2

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