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Urine Methylation Markers in UTUC

RECRUITINGN/ASponsored by Duke University
Actively Recruiting
PhaseN/A
SponsorDuke University
Started2025-05-07
Est. completion2026-06
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT06805630

Summary

This is a research study to measure DNA markers in the urine of patients with upper tract urothelial cancer (UTUC) before surgery and during follow-up visits. Identifying these DNA markers could improve diagnosis before surgery, help assess risk, and predict early recurrence of the cancer. Urine samples will be de-identified and sent to Pangea Laboratory LLC for analysis. The results of this test will be compared to the traditional tests in upper tract urothelial cancer, such as cells in the urine and tissue biopsy.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* \>=18 years
* Primary UTUC

Exclusion Criteria:

* Patients who do not understand and/or are unwilling to sign a written informed consent

Conditions2

CancerUpper Tract Urothelial Cancer

Locations1 site

Duke University
Durham, North Carolina, 27710
Alireza Ghoreifinejadian, M.D.919-684-8111alireza.ghoreifi@duke.edu

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