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Comparison of Clomid and Lezra With Lezra for Ovulation Induction in Clomid Resistant PCOS Case

RECRUITINGPhase 1Sponsored by HITEC-Institute of Medical Sciences
Actively Recruiting
PhasePhase 1
SponsorHITEC-Institute of Medical Sciences
Started2024-06-07
Est. completion2025-02
Eligibility
Age20 Years – 40 Years
SexFEMALE
Healthy vol.Accepted

Summary

Clomiphene citrate resistant i.e failure to ovulate after 6 cycles of ovulation induction effects 15-40% of patients with PCOS.Two treatment groups will be formed one recieving letrozole alone and another recieving CC and letrozole combined.Mature follicles and endometrial thickness will be checked by transvaginal ultrasound and results will be recorded.

Eligibility

Age: 20 Years – 40 YearsSex: FEMALEHealthy volunteers accepted
Inclusion Criteria:

* women of 20-40 years with a history of PCOS and resistant to CC

Exclusion Criteria:

* Premature ovarian insufficiency
* Husband has oligo azoospermia
* Hypothyroidism
* Hyperprolactinemia

Conditions2

CancerPolycystic Ovarian Syndrome

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