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Prognostic Factors for HCC and Liver Transplantation in Patients With MASLD/MASH

RECRUITINGSponsored by IRCCS Azienda Ospedaliero-Universitaria di Bologna
Actively Recruiting
SponsorIRCCS Azienda Ospedaliero-Universitaria di Bologna
Started2024-11-20
Est. completion2043-11-20
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

The BOMASH study is a single-center, prospective/retrospective observational study without pharmacological interventions. It will include all patients diagnosed with Metabolic-Associated Steatotic Liver Disease (MASLD/MASH), whether newly diagnosed or previously identified at the center during follow-up or as part of routine diagnostic and therapeutic care. The aim of the study is to identify predictive factors related to the prognosis of patients with metabolic liver disease (MASLD/MASH). Specifically, the study seeks to uncover biomarkers that can identify individuals at risk of requiring a liver transplant or developing HCC.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* All patients with a diagnosis of MASLD, established according to the most recent published guidelines (EASL, EASD, EASO)
* Age ≥18 years

Inclusion Criteria for Biological Sample Collection:

* Patients requiring liver biopsy for diagnostic purposes, as indicated by the most recent published guidelines (EASL, EASD, EASO)

Exclusion Criteria:

* No exclusion criteria.

Conditions7

CancerHepatocellular CarcinomaLiver CancerLiver DiseaseLiver TransplantMetabolic Dysfunction-Associated SteatohepatitisMetabolic Dysfunction-Associated Steatotic Liver Disease

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