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Influence of Sarcopenia on the Course of the Diseases

RECRUITINGSponsored by Universitatsmedizin Mainz - 1. Medizinische Klinik
Actively Recruiting
SponsorUniversitatsmedizin Mainz - 1. Medizinische Klinik
Started2024-10-01
Est. completion2026-10-01
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06829290

Summary

Frailty is a geriatric syndrome that primarily affects older patients, but also patients with severe illnesses. It is particularly common among oncology patients, but also among patients with gastrointestinal diseases such as liver cirrhosis or pancreatitis. Sarcopenia, a form of frailty, is defined as a loss of muscle quantity, quality and function. Currently, complex methods such as CT or bioimpedance measurement are available. However, simpler techniques such as ultrasound-based measurement could be alternatives, but still require further validation. In addition, serological muscle markers could support and simplify diagnostics. The aim of this project is to be able to estimate the prognosis of patients at an early stage by measuring sarcopenia using ultrasound and biomarkers.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* oncological patient in the field of gastrointestinal tumors
* patients with liver cirrhosis
* patients attending the intensive care unit

Exclusion Criteria:

* patients incapable of consenting
* patients with congenital muscle diseases

Conditions8

CachexiaCancerLiver CancerLiver CirrhosisLiver DiseaseMechanical VentilationSarcopeniaWeight Loss

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