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Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer

RECRUITINGPhase 2Sponsored by EXACT Therapeutics AS
Actively Recruiting
PhasePhase 2
SponsorEXACT Therapeutics AS
Started2025-06-19
Est. completion2026-12-15
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations7 sites
View on ClinicalTrials.gov →

NCT06850623

Summary

The purpose of the study is to assess the efficacy and safety of Acoustic Cluster Therapy (ACT) when given in addition to chemotherapy for treatment of Locally Advanced Pancreatic Cancer.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Not deemed suitable for primary curative surgery and have radiographic and pathological disease consistent with inoperable LAPC or borderline resectable pancreatic cancer.
* Suitable to receive treatment with mFOLFIRINOX according to the Investigator's assessment.

Exclusion Criteria:

• Any prior anti-cancer treatment for pancreatic cancer (e.g. chemotherapy, surgery, radiation). Palliative bypass procedure and bile duct stenting are allowed.

Conditions2

CancerLocally Advanced Pancreatic Adenocarcinoma

Locations7 sites

HonorHealth Research Institute
Scottsdale, Arizona, 85258
Lu Study Coordinator(+1) (480) 323 1364clinicaltrials@honorhealth.com, lzhao@honorhealth.com
Stanford Cancer Center Palo Alto
Stanford, California, 94305
Beth Israel Deaconess Medical Center - Division of Hematology/Oncology
Boston, Massachusetts, 02215
Henry Ford Centre
Detroit, Michigan, 48202
Sidney Kimmel Cancer Center, Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, 19107

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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