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Combating Cancer-Related Fatigue: A Personalized Supportive Care Program

RECRUITINGN/ASponsored by UNC Lineberger Comprehensive Cancer Center
Actively Recruiting
PhaseN/A
SponsorUNC Lineberger Comprehensive Cancer Center
Started2025-06-03
Est. completion2026-12-31
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site

Summary

This health services study will assess a multidisciplinary intervention program directed at fatigue mitigation among patients diagnosed with indolent lymphomas. Specifically, 30 subjects with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and 10 subjects with Follicular Lymphoma (FL), marginal zone lymphoma (MZL), lymphoplasmacytic lymphoma (LPL), Waldenström's Macroglobulinemia, or Cutaneous T Cell Lymphoma (CTCL) will be included.

Eligibility

Age: 18 Years+Healthy volunteers accepted
In order to participate in this study a subject must meet all of the eligibility criteria outlined below.

Inclusion Criteria:

* Written informed consent was obtained to participate in the study and HIPAA authorization for the release of personal health information.
* Subjects are willing and able to comply with study procedures based on the judgment of the investigator.
* Age ≥ 18 years at the time of consent.
* Confirmed diagnosis of indolent lymphoma, Waldenström's Macroglobulinemia, or Cutaneous T Cell Lymphoma.
* Significant symptoms of fatigue, as defined by PROMIS Fatigue score \>50.

Exclusion Criteria:

* Other co-existing malignancies.
* Significant cognitive impairment as defined by Mini-Cog score 0-2 (out of 5) that would prevent understanding of assessments or interventions.
* Unstable or serious illness (e.g., unstable cardiac arrhythmia, severe anemia/thrombocytopenia) that would prevent safe participation in an exercise regimen, per the discretion of the treating physician.
* Individuals who are not able to consume an oral diet, due to swallowing difficulties or other reasons, as this might interfere with the nutritional intervention

Conditions10

CancerChronic Lymphocytic LeukemiaCutaneous T Cell LymphomaFollicular LymphomaIndolent LymphomasLymphomaLymphoplasmacytic LymphomaMarginal Zone LymphomaSmall Lymphocytic LymphomaWaldenstrom Macroglobulinemia

Locations1 site

North Carolina Basnight Cancer Hospital
Chapel Hill, North Carolina, 27514
Devin McCarthy919-445-4852devin_mccarthy@med.unc.edu

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