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Pre-malignant States to Hematologic Malignancies in Firefighters

RECRUITINGSponsored by Wake Forest University Health Sciences
Actively Recruiting
SponsorWake Forest University Health Sciences
Started2026-03
Est. completion2027-04
Eligibility
Age40 Years – 49 Years
Healthy vol.Accepted
Locations1 site

Summary

The purpose of the study is to evaluate if firefighter exposure to hazardous compounds will increase the incidence of premalignant hematological states which subsequently increases the risk of the development of hematologic malignancies, and potentially other pathophysiological consequences.

Eligibility

Age: 40 Years – 49 YearsHealthy volunteers accepted
Inclusion Criteria:

1. Written informed consent and HIPAA authorization for release of personal health information.
2. Age ≥ 40-49 years at the time of consent (self-reported)
3. Ability of the participant to understand and comply with study procedures for the entire length of the study
4. Currently employed by Charlotte Fire Department (CFD) with at least 5 years on-the -job experience (self-reported)

Exclusion Criteria:

Anyone with a current diagnosis of a hematologic malignancy will be excluded.

Conditions7

CancerClonal Hematopoiesis of Indeterminate PotentialLeukemiaMonoclonal GammopathyMultiple MyelomaNon-hodgkin LymphomaPlasma Cell Disorder

Locations1 site

Levine Cancer Institute
Charlotte, North Carolina, 28204
Megan Lattanze980-442-4239Megan.Lattanze@advocatehealth.org

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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