Impact of Prehabilitation in Oncology Via Exercise- Esophageal (IMPROVE-Esophageal)

Summary

The goal of this study is to determine the feasibility of a prehabilitation exercise and nutrition program (exercise and nutrition before a medical treatment) in adults with esophageal cancer before surgery (esophagectomy). The pre-surgery exercise and nutrition program will include resistance and aerobic training and nutrition supplementation during the weeks before surgery. We will also assess pre-surgical care needs in adults with esophageal cancer. Researchers will compare the exercise and nutrition intervention to usual care- which is standard medical care and post-surgery surveillance/follow-up to understand the impact of exercise and nutrition before surgery. We will follow-up with participants before surgery, and after surgery at 2 weeks, 6 weeks, and 4-months at appointments that coincide with clinical follow-ups. The main questions of this trials are: * Is exercise and nutrition supplementation before surgery for esophageal cancer feasible and acceptable to patients? * How does exercise and nutrition supplementation before surgery change physical function and psychosocial health? * What are important pre-surgical needs for adults with esophageal cancer?

Eligibility

Inclusion Criteria:

* Men and women, age ≥ 18 years old
* Diagnosed with esophageal cancer
* Identified as esophagectomy surgery candidates at Hillman Cancer Center or UPMC Shadyside
* ≥ 2 weeks until scheduled esophagectomy
* ECOG Performance Status Scale score of ≤ 2
* Ability to provide written informed consent
* Ability to understand, speak, and read English.

Exclusion Criteria:

* Evidence in the medical record of an absolute contraindication for exercise (e.g., Heart insufficiency \> NYHA III or uncertain arrhythmia; uncontrolled hypertension; reduced standing or walking ability)
* Any other comorbidities or musculoskeletal complications that preclude participation in the exercise programs as deemed by the exercise interventionist
* Receiving non-esophagectomy related chemotherapy and/or radiotherapy
* Active infections, hemorrhages, and cytopenias that could place surgical patients at risk for further adverse events, deemed by the exercise interventionist, physician, and/or nurse

Conditions3

Locations1 site

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