Efficacy of Ultrasound-Guided Genicular Nerve Radiofrequency Ablation Therapy

Summary

The main symptom of knee osteoarthritis, which occurs after damage to the joint cartilage with age, is pain, but this symptom often becomes chronic. Current conservative treatments have moderate effects on chronic knee pain and their use is limited due to the risk of side effects. In addition to pain, patients also experience other symptoms. As a result of the osteoarthritis process, prorioception in the knee is impaired with a decrease in mechanoreceptors, resulting in loss of balance and an increase in the risk of falling.

Eligibility

Inclusion Criteria:

* Age between 30-75
* Chronic knee pain that lasts at least 6 months
* Radiographic confirmation of osteoarthritis: Presence of Grade 3 or 4 radiographic changes characterized by significant narrowing in the medial space of the tibiofemoral joint according to the Kellgren-Lawrence classification system
* Knee pain \>40 mm when performing one of the two movements that cause the most severe pain (sitting to standing or going up and down stairs) according to 100 mm VAS

  * 50% reduction in VAS with diagnostic genicular nerve block

Exclusion Criteria:

* Presence of systemic inflammatory disease such as rheumatoid arthritis
* Previous RFA treatment to the knee or hyaluronic acid or steroid injection to the knee within the last 3 months
* History of previous knee surgery
* Clinically significant structural abnormalities other than osteoarthritis that may lead to chronic knee pain
* Having undergone physical therapy to the knee in the last 6 months or a history of knee trauma
* Application of other pain treatments
* Body-Mass İndex \<18 and \>40 kg/m2
* Pregnancy
* Presence of uncontrolled serious illness (cancer, diabetes, etc.), infection, psychiatric disorder, coagulation disorder

Conditions2

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