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HLA Antibodies in Systemic Lupus Erythematosus

RECRUITINGSponsored by Centre Hospitalier Universitaire, Amiens
Actively Recruiting
SponsorCentre Hospitalier Universitaire, Amiens
Started2025-02-10
Est. completion2026-11
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06921239

Summary

Patients suffering from autoimmune diseases show false-positive results when anti-HLA antibodies are identified. This false positivity makes it difficult to obtain an organ transplant based on immunological compatibility (absence of anti-HLA antibodies directed against graft antigens). The objectives of this project are to study the prevalence of these false positivities in a population of lupus patients, and to evaluate biological tests that can negate these false positivities.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Patients Adults
* Followed in the internal medicine department of Amiens University Hospital - With systemic lupus erythematosus
* Without HLA immunization risk factors (no history of pregnancy, transfusions or transplants)
* With sera stored in the biobank

Exclusion Criteria:

* minor Patients
* Opposing the re-use of their personal data for research purposes

Conditions3

HLA AntibodiesLupusSystemic Lupus Erythematosus

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