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Cancer of the Lung And SeneScencE - Prospective Cohort 1

RECRUITINGN/ASponsored by Assistance Publique - Hôpitaux de Paris
Actively Recruiting
PhaseN/A
SponsorAssistance Publique - Hôpitaux de Paris
Started2025-07-09
Est. completion2028-07
Eligibility
Age70 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06923618

Summary

The main objective is to identify and assess the predictive value of ageing and senescence biomarkers (methylome, telomeres, inflammageing) and senescent cells in tissues to improve prognosis assessment older patients with locally or locally-advanced Non-Small Cell Lung Cancer (NSCLC).

Eligibility

Age: 70 Years+Healthy volunteers accepted
Inclusion Criteria:

* Patients 70 years and over
* Local or locally advanced (Clinic stage I-IIIA) NSCLC (clinically (or radiologically) suspected or histologically proven)
* Surgical Curative Intent
* Signed informed Consent (or signed by the curator or tutorship)
* Affiliated to social security administrative care service

Exclusion Criteria:

* Synchronous cancer (histologically proven or strongly suspected non-lung cancer in the 6 months prior to inclusion (excluding basal cell cancer and prostate cancer with local treatment (radiotherapy or surgery) or active surveillance without systemic treatment (chemotherapy, hormone therapy)).
* Subject deprived of liberty by judicial or administrative decision or patient under guardianship
* Subject unable to understand the purpose and conditions of the study and unable to give consent

Conditions3

CancerLung CancerNon Small Cell Lung Cancer

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