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Rate of Malignant Transformation and Clinical Characteristics Among an Oral Lichen Planus Cohort: a Retrospective Center Experience

RECRUITINGSponsored by Catholic University of the Sacred Heart
Actively Recruiting
SponsorCatholic University of the Sacred Heart
Started2024-01-31
Est. completion2028-01-31
Eligibility
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06934863

Summary

The main objective of this paper will be to evaluate the rate of malignant transformation among a cohort of patients affected by oral lichen planus with long-term follow-up. Secondary aims will be to study and describe the characteristics of these patients to identify potential risk factors for malignant transformation, and to evaluate the therapeutic effects and features to OLP drgus.

Eligibility

Healthy volunteers accepted
Inclusion Criteria:

* Clinical-histological diagnosis of Oral lichen planus
* Patients who gave consensus to personal data treatment
* Minimum 6 months follow-up

Exclusion Criteria:

* Patients who did not give consensus to personal data treatment
* Oral lichenoid lesions
* Patients with anamnesis of hematopoietic stem cells transplant
* Patients with a OSCC at the first histological examination (i.e., namely: also OSCC patients with a OLP background were excluded)

Conditions4

CancerOral CarcinomaOral Carcinoma in SituOral Lichen Planus

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