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Improving Functional Outcomes and Quality of Life in Patients With Rectal Cancer After Surgery With Intensified Follow-up & Surveillance

RECRUITINGPhase 3Sponsored by University Hospital, Basel, Switzerland
Actively Recruiting
PhasePhase 3
SponsorUniversity Hospital, Basel, Switzerland
Started2025-12-01
Est. completion2028-05-01
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

The goal of this clinical study is to gain further insights into the treatment of patients with Low Anterior Resection Syndrome (LARS) symptoms after rectal resection. The main question is: Can LARS symptoms and quality of life be improved by implementing an intensified follow-up program? Researchers will compare the results of the intervention group with the results of a control group in which patients do not receive an intensified follow-up program to determine whether the intervention works. Participants will undergo an intensified follow-up program which consists of several follow-up visits and medical treatment, pelvic floor muscle training and gynaecological and urological co-treatment in case of LARS symptoms and urinary or sexual complaints.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* patients older than 18 years
* patients with rectal cancer in the middle and lower third of the rectum in stages I to IV who underwent LAR with TME and protective ileostomy
* able to give informed consent as documented by signature

Exclusion Criteria:

* dementia or other psychiatric disorder that would prevent the patients from answering the questionnaires and experiencing sustainable training effects
* impossibility of stoma reversal due to persistent anastomotic leak and/or local recurrence

Conditions5

CancerLARS - Low Anterior Resection SyndromeQuality of Life (QOL)Rectal CancerRectal Cancer Surgery

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