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Use of Extracellular Vesicles (EV) for Knee Osteoarthrosis

RECRUITINGPhase 1Sponsored by University of Jordan
Actively Recruiting
PhasePhase 1
SponsorUniversity of Jordan
Started2024-01-01
Est. completion2026-01-30
Eligibility
Age42 Years – 75 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06937528

Summary

Extracellular vesicles (EV) will be injected in patients diagnosed with Knee osteoarthrosis

Eligibility

Age: 42 Years – 75 YearsHealthy volunteers accepted
Inclusion Criteria:

* Severe KOA stage III or IV by Laurance \& Kellgren staging as judged by Posterioranterior (PA) Xray of the knee joint.
* Willing to participate by signing the informed consent

Exclusion Criteria:

* Sublaxation beyond 20 degrees of the bones of the knee joint
* Oral anticoagulants or heparin therapy
* Heart failure or arrhythmia
* Body Mass Index \> 35
* Uncontrolled Diabetes Mellitus.
* Evidence of Infectious Diseases.
* Active infection
* Malignancy
* Pregnancy
* Anemia less than 11g/dl or thrombocytopenia less than 100,000 or leucopenia less than 3000.
* Unreliable patients
* Non-resident in Jordan

Conditions2

ArthritisKnee Osteoarthrosis

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