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Randomized Controlled Trial of the Effects of Combined Resistance and AerobiC Exercise on Health-related Quality of Life in Patients Undergoing First-line Chemotherapy for Metastatic Colorectal Cancer (REACH)

RECRUITINGN/ASponsored by Rigshospitalet, Denmark
Actively Recruiting
PhaseN/A
SponsorRigshospitalet, Denmark
Started2025-05-16
Est. completion2027-05-01
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06938971

Summary

The primary objective of this trial is to compare the effects of 18 weeks structured exercise training versus on control on healt-related quality of life in patients with unresectable mCRC.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion criteria:

\- Adults (≥18 years of age) schduled to undergo chemotherapy for the treatment of unresectable metastatic colorectal cancer.

Exclusion criteria :

* Pregnancy.
* A life expectancy of \< 6 months.
* Absolute contraindications to maximal exercise, as per the recommendations by the Danish Society of Cardiology.
* ECOG (Eastern Cooperative Oncology Group) performance status \> 2.
* Inability to understand the Danish or English language.
* Engagement in structured moderate-to-high aerobic exercise training for \>30 min \>1 times/week for the past 3 months at the time of inclusion.

Conditions2

CancerMetastatic Colorectal Cancer (mCRC)

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