|

Intraoperative Hypotension in Pancreatoduodenectomy: A Randomized Trial of General Versus Combined Anesthesia

RECRUITINGN/ASponsored by Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Actively Recruiting
PhaseN/A
SponsorInstituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Started2025-04-07
Est. completion2030-01-07
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06953193

Summary

This randomized clinical trial compares the hemodynamic effects of general anesthesia versus combined general anesthesia (thoracic epidural) in patients undergoing pancreatoduodenectomy. The primary aim is to assess the incidence of intraoperative hypotension and related adverse events. Secondary outcomes includes vasopressor requirements, transfusion needs, postoperative complications, intensive care unit admission, hospital length of stay, and mortality.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Signed written informed consent.
* Patients scheduled for elective pancreatoduodenectomy at National Institute of Medical Sciences and Nutrition Salvador Zubirán.
* No contraindications for neuroaxial anesthesia (epidural catheter placement), including:

  * Generalized or localized infection at the puncture site.
  * Thrombocytopenia.
  * Coagulation disorders.
  * Intracranial hypertension.
  * Patient refusal.

Exclusion Criteria:

* Age under 18 years.
* Pregnancy.
* Inability to randomize the case due to specific circumstances (such as contraindications to epidural use), resulting in non-eligibility based on participation criteria.

Conditions4

CancerHypotensionPancreatic NeoplasmsPancreatoduodenectomy

Browse More Trials

Cancer trials

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

This site does not provide medical advice. Always consult your doctor before considering enrollment in a clinical trial. Learn more on our About page.