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Outcomes Following Limb Sparing Surgery for Soft Tissue Sarcoma

RECRUITINGSponsored by Amsterdam UMC
Actively Recruiting
SponsorAmsterdam UMC
Started2025-04-24
Est. completion2028-01-01
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

The goal of this study is to assess body image, health-related quality of life (QoL), and functioning (gait function, joint function, and walking ability) in patients after resection of localized soft tissue sarcoma (STS) of the extremities. A secondary objective is to assess the influence of different variables (e.g., radiotherapy, ethnicity, etc.) on body image, health-related QoL, and functioning. Patients who underwent a surgical resection at the Amsterdam UMC between 2010 and 2021 will be approached to participate in the study. Participants will complete four questionnaires and undergo a physical examination. Additionally, they will have a 3D gait analysis, a 6-minute walk test with gas analysis, and a muscle strength assessment. Furthermore, muscle volume change will be evaluated on pre- versus postoperative MRI scans.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Treated with surgical resection for primary non-metastatic extremity STS at the Amsterdam UMC between 2010-2021.
* Being able to visit the Amsterdam UMC, location AMC once or twice.
* Pregnant patients must agree to be scheduled 5 months after their pregnancy ends.

Exclusion Criteria:

* Patients who cannot maintain 6 minutes of walking will be excluded from the 6-minute walk test.

Conditions2

CancerSoft Tissue Sarcoma

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