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Raman Spectroscopy in the Diagnosis of Extrahepatic Cholangiocarcinoma - a Pilot Study

RECRUITINGN/ASponsored by University Hospital Olomouc
Actively Recruiting
PhaseN/A
SponsorUniversity Hospital Olomouc
Started2023-02-04
Est. completion2025-05-31
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

Diagnosis of extrahepatic cholangiocarcinoma is challenging because the yield of imaging and tissue sampling is limited. Raman spectroscopy is an optical method based on the analysis of scattered monochromatic light. Raman spectroscopy is able to provide a molecular 'fingerprint' of the tissue to determine its type. The aim of this pilot study was to develop a methodology for in vivo Raman spectroscopy in bile ducts to improve the current diagnostic capabilities of extrahepatic cholangiocarcinoma.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* person older than 18 years, who has known extrahepatic cholangiocarcinoma and is indicated for ERCP

Exclusion Criteria:

* disagreement with the study

Conditions10

Biliary StrictureCancerCholangiocarcinoma of the Extrahepatic Bile DuctCholangiocarcinoma, ExtrahepaticCholangiocarcinoma, PerihilarDiagnosisEndoscopyKlatskin TumorMalignant Biliary StrictureRaman Spectroscopy

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