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Early-Onset Colorectal Cancer: An Observational Retrospective and Prospective Multicenter Study

RECRUITINGSponsored by Niguarda Hospital
Actively Recruiting
SponsorNiguarda Hospital
Started2024-04-17
Est. completion2026-12-31
Eligibility
Age18 Years – 40 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06965335

Summary

Observational, retrospective and prospective multicentric Italian study of patients diagnosed with colorectal cancer between age 18-40, aiming at underpinning the biology of vEO-CRC, including colibactin as well as a broader proteo-genomic characterization, to identify potential new therapeutic targets specifically directed to this peculiar subset of patients.

Eligibility

Age: 18 Years – 40 YearsHealthy volunteers accepted
1. Patients with diagnosis of colorectal cancer (vEO-CRC: 18-40 years of age), or SO-CRC diagnosed later than age 60;
2. Informed consent signature from alivepatient;
3. Availability of formalin-fixed paraffin embedded (FFPE) tumor samples (5 FFPE 4uM thick slides and 10 FFPE 10 uM thick slides) and/or fresh tumor tissue retrieved from a biopsy or surgical procedure performed as per clinical standard of care.

Conditions2

CancerColo-rectal Cancer

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