Multiprofen-CC to Reduce Pain in Hand Arthritis

Summary

This clinical trial aims to find out if using 1 gram of Multiprofen-CC cream on the hands three times a day for 4 weeks can help reduce pain in adults with hand osteoarthritis, compared to a placebo (a cream with no active medicine). The research team will also look at how Multiprofen-CC affects hand function, opioid use, and how patients feel about their overall improvement. In addition, the research team will keep track of any side effects. Participants will: * Use both Multiprofen-CC and a placebo (a cream with no active medicine) during the study, in a random order. * Be asked to apply 1 gram of cream to their hands three times a day for 2 weeks, following the manufacturer's instructions. * Attend a visit before starting the study, after 2 weeks, and after 6 weeks. * Report any symptoms they experience during the study.

Eligibility

Inclusion Criteria:

* Adults (18+)
* Have been diagnosed with hand osteoarthritis according to American College of Rheumatology criteria
* Experience pain and/or loss of function in one or both hands that interferes with daily life
* Provide informed consent

Exclusion Criteria:

* Unable to consent
* Unable or unwilling to follow study protocol
* Known allergy or contraindication to any of the study drugs or their ingredients
* Have open wounds/cuts and/or skin conditions on the hand area
* Pregnant or breastfeeding
* History of impaired kidney or liver function
* Rheumatoid or other inflammatory arthropathy
* Hand surgery within the past 6 months or planned within the study period.
* Use daily opioids (other than short acting codeine) for a chronic pain condition other than hand arthritis

Conditions2

Interventions1

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