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CTFFR and Prediction of Non-Significant CAD Lesions

RECRUITINGN/ASponsored by Shiraz University of Medical Sciences
Actively Recruiting
PhaseN/A
SponsorShiraz University of Medical Sciences
Started2024-01-01
Est. completion2026-07-01
Eligibility
Age20 Years – 80 Years
Healthy vol.Accepted

Summary

In this prospective cohort study, 250 patients with suspected or known CAD and at least one intermediate coronary lesion (50-70% stenosis) who had a NiFFR value greater than 0.80 underwent coronary computed tomography angiography (CCTA) with NiFFR assessment. Patients were followed for one year to monitor for MACE

Eligibility

Age: 20 Years – 80 YearsHealthy volunteers accepted
Inclusion Criteria:

* Patients were enrolled if they had at least one intermediate coronary lesion (classified as 50-70% diameter stenosis on visual judgment) on CCTA and then underwent FFR testing

Exclusion Criteria:

* Patients having past coronary artery bypass graft surgery (CABG)
* previous PCI in the target vascular
* significant renal impairment define with eGFR \< 30 mL/min/1.73 m²
* contrast allergy
* poor image quality that prevented appropriate CCTA or CT-FFR analysis

Conditions2

Chronic Coronary SyndromeHeart Disease

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