Optimizing Mango's Glycemic Impact: Investigating Mango Consumption Timing in Prediabetic Individuals

Summary

The purpose of this study is to investigate the effect of mango intake on metabolic and inflammatory responses relative to meals in individuals at risk of developing diabetes, as well as to understand how the beneficial compounds found in mangoes are absorbed and processed in the body.

Eligibility

Inclusion Criteria:

* Be between 20-60 years old.
* Have a BMI of 25-35 kilograms per square meter.
* Have fasting blood glucose between 100-125 milligrams per deciliter or Glycated hemoglobin (HbA1c) between 5.7-6.4%.
* Be non-smokers for at least 12 months.
* Be generally healthy, with no major organ-related diseases.
* Not take medications or supplements that could interfere with the study.
* Be able to follow study procedures, including dietary restrictions and scheduled visits.

Exclusion Criteria:

* Smoke, vape, or use marijuana.
* Have allergies or intolerance to mangoes or study foods.
* Have blood pressure above 160/100 millimeters of Mercury.
* Have fasting blood glucose above 125 milligrams per deciliter.
* Have a history of major heart disease, stroke, or cancer in the past five years.
* Be pregnant, planning to become pregnant, or breastfeeding.
* Take anti-inflammatory drugs or certain dietary supplements.
* Have had major surgery or trauma in the past two months.
* Follow extreme diets (e.g., vegan, Atkins).
* Have used antibiotics in the last six weeks.
* Have a history of eating disorders or substance abuse in the past two years.
* Drink more than three cups of coffee or tea per day.
* Have donated blood in the last three months.
* Be professional athletes or do excessive exercise.
* Have had weight changes of more than 11 pounds in the past two months.
* Work overnight shifts.

Conditions2

Locations1 site

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