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Post Prandial Individual Responses to Different Foods

RECRUITINGN/ASponsored by Stanford University
Actively Recruiting
PhaseN/A
SponsorStanford University
Started2025-10-01
Est. completion2028-11-30
Eligibility
Age18 Years – 80 Years
Healthy vol.Accepted
Locations1 site

Summary

This study aims to understand why people respond differently to the same foods, especially when it comes to changes in blood sugar after eating. A continuous glucose monitors (CGMs) will be used to observe how individuals respond to specific meals and drinks (e.g., Oral Glucose Tolerance Test, OGTT). By studying these patterns, the investigators hope to identify different types of metabolism and see if certain foods or food ingredients (like fiber, amino acids, or vinegar) can help control blood sugar better for specific groups. This research will help lay the groundwork for personalized dietary advice based on a person's unique biology.

Eligibility

Age: 18 Years – 80 YearsHealthy volunteers accepted
Inclusion Criteria:

* BMI (body mass index) \>19 kg/m2 but \< 45 kg/m2
* HbA1c \< or equal to 7.0% while not on antihyperglycemic medications
* Be willing to provide written informed consent for all study procedures.
* Able to commute to Stanford campus for on-site visits

Exclusion Criteria:

* recent (\<6mos) CVD (cardiovascular disease) event
* active malignancy
* kidney/liver disease
* pregnancy/lactation
* chronic inflammatory disease
* eating disorder
* bariatric surgery
* history of acute pancreatitis
* current use of antihyperglycemic, diabetogenic, or weight loss medications
* heavy alcohol use
* physical activity \>2 hours/day
* inability to come to Stanford CTRU (Clinical and Translational Research Unit) for metabolic testing

Conditions4

DiabetesDiabetes Mellitus, Type 2HealthyPreDiabetes

Locations1 site

Stanford University
Stanford, California, 94304
Sabrina Chun Johnston, MS, RD(650) 725-0169csjohn@stanford.edu

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