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Smart Measurement of Circulating Tumor DNA

RECRUITINGN/ASponsored by Erasmus Medical Center
Actively Recruiting
PhaseN/A
SponsorErasmus Medical Center
Started2025-05-16
Est. completion2026-10-01
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06989814

Summary

The goal of this study is to develop a blood-test which can detect colorectal cancer in early stages. Participants will be asked to take an extra blood test, which will be analyzed further in the lab.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

(suspect) Lynch Syndrome carriers who:

* Have proven Lynch Syndrome (MMR-gene or EPCAM mutation), or have a proven microsatellite instability high (MSI-H)tumor;
* Are at least 18 years old; Have been diagnosed with any form of cancer at the time of inclusion, but have had no treatment yet;
* Have granted informed consent to participate in this study.

Exclusion Criteria:

(suspect) Lynch Syndrome carriers who:

* Are unwilling to undergo extra blood sampling;
* Are under the age of 18;
* Have no newly diagnosed tumors at time of inclusion;
* Have been treated for their tumor at time of inclusion;
* Are not able to read or understand Dutch language or are mentally not capable.

Conditions5

CancerColorectal NeoplasmsColorectal Neoplasms MalignantColorectal Neoplasms, Hereditary NonpolyposisHereditary Nonpolyposis Colon Cancer

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