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Correlation of STN-DBS Induced Visuospatial Changes and Freezing of Gait

RECRUITINGN/ASponsored by Medical University of South Carolina
Actively Recruiting
PhaseN/A
SponsorMedical University of South Carolina
Started2025-04-01
Est. completion2026-06
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT06994728

Summary

The purpose of this research is to determine how deep brain stimulation (DBS) for Parkinson's disease affects attention and visuospatial function. Additionally, this study will evaluate how deficits in visual attention are associated with freezing of gait (FOG) in Parkinson's disease. There is currently no reliable treatment for FOG and little is understood about the underlying reason this occurs. Some recent research has found that stimulating the right side of the brain seems to improve FOG. The right side of the brain is also paramount for visual attention, which is why investigators are conducting this study.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Subjects above 18 years of age
* Subjects with freezing of gait
* Subjects with bilateral STN-DBS surgery as part of their clinical care for Parkinson's disease

Exclusion Criteria:

* Uncorrected visual or hearing impairments, as indicated by self-report
* Individuals who are pregnant or expect to become pregnant during the course of the study
* Individuals with dementia or relevant brain lesions impacting cognition or gait

Conditions4

Gait Disorders, NeurologicParkinson DiseaseParkinson's DiseaseVisuospatial/Perceptual Abilities

Locations1 site

Medical University of South Carolina
Charleston, South Carolina, 29403
Nathan DeTurk, MD, MBA843-792-3221deturk@musc.edu

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