|

Comparison of Drainage Methods in Minimally Invasive Esophagectomy (DEMURE）

RECRUITINGN/ASponsored by Ruijin Hospital
Actively Recruiting
PhaseN/A
SponsorRuijin Hospital
Started2025-04-30
Est. completion2026-05-01
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07004634

Summary

This RCT compares three drainage approaches after minimally invasive esophagectomy (chest tube + thoracic mediastinal drainage tube, thoracic, and abdominal mediastinal drainage tube) to evaluate perioperative outcomes, addressing current evidence gaps in pain and complication profiles.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Age ≥18 years
* Pathologically confirmed esophageal cancer requiring three-incision esophagectomy (cervical, thoracic, and abdominal incisions)
* ASA physical status class I-III

Exclusion Criteria:

* History of chronic pain or long-term use of analgesics prior to surgery
* Severe cardiopulmonary dysfunction (e.g., FEV1 \<50%)
* Coagulation disorders or patients undergoing reoperation
* Intraoperative findings of extensive pleural adhesions, combined resection of adjacent organs, or other conditions deemed by the investigator to warrant exclusion

Conditions4

CancerDrainage/MethodsEsophageal CancerPostoperative Pain

Browse More Trials

Cancer trials

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

This site does not provide medical advice. Always consult your doctor before considering enrollment in a clinical trial. Learn more on our About page.