SNU IBD Cohort Study : Searching for Characterization of High Risk Populations for Developing Inflammatory Bowel Disease

Summary

The goal of this observational study is to investigate characteristics of individuals at high risk for developing Inflammatory Bowel Disease (IBD) in order to identify risk factors associated with its incidence. The main question it aims to answer is: What are the risk factors for developing Inflammatory Bowel Disease? Researchers will compare groups at high risk for IBD to healthy populations and to patients already diagnosed with IBD. Participants will * undergo assessments of general demographic and clinical characteristics. * be monitored for symptoms using questionnaires administered at regular intervals. * have blood tests and stool examinations performed. In cases where participants undergo colonoscopy for routine clinical indications, gut biopsies will also be performed.

Eligibility

Inclusion Criteria:

* first-degree relatives of Inflammatory Bowel Disease patients
* patients who are diagnosed with autoimmune diseases
* patients with functional gastrointestinal disorders who are ASCA-positive

Exclusion Criteria:

* Patients with symptoms such as a 10% weight loss within 3 months, abdominal pain, hematochezia, or diarrhea will undergo colonoscopy, and those diagnosed with Inflammatory Bowel Disease will be excluded.
* Treatment history of Diabetes Mellitus, Irritable Bowel Syndrome, or colon cancer.

Conditions2

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