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Prehab and Creatine/Whey Supplementation in Frailty Among Patients With Cirrhosis

RECRUITINGN/ASponsored by University of California, San Francisco
Actively Recruiting
PhaseN/A
SponsorUniversity of California, San Francisco
Started2026-04-15
Est. completion2026-12
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site

Summary

Frailty and muscle health are important for patients with chronic liver disease. This study looks at the use of a digital prehabilitation app (HEAL-ME) plus creatine and whey protein combination supplementation on maintaining muscle health in patients with liver disease. The investigators anticipate that this combination of supplementation and nutrition/exercise prehabilitation app will maintain muscle health in patients with liver disease.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Confirmed diagnosis of cirrhosis by ICD-10 code, liver biopsy, abdominal imaging, or transient elastography
* Access to digital device and internet at home
* Ability to provide written informed consent before any study-related activities
* Ability to remain in study for at least 3 months

Exclusion Criteria:

* Allergy to milk protein
* On hemodialysis
* No English language proficiency
* Presence of condition or abnormality that in opinion of the Investigator will compromise safety of the patient or quality of the data
* Concomitant severe underlying systemic illness that in the opinion of the Investigator would interfere with completion of study
* Pregnant, breastfeeding, or intention of becoming pregnant during study time frame

Conditions4

CirrhosisFrailtyLiver DiseaseSarcopenia

Locations1 site

University of California San Francisco
Melinda Wang, MD, MHS415-476-2777melinda.wang3@ucsf.edu

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