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An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.

RECRUITINGPhase 2Sponsored by NGM Biopharmaceuticals, Inc
Actively Recruiting
PhasePhase 2
SponsorNGM Biopharmaceuticals, Inc
Started2025-06
Est. completion2027-04
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site

Summary

A multi-center evaluation of NGM120 in a randomized, double-blind, placebo-controlled study in participants with colorectal cancer who have cancer cachexia.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

1. Documented active diagnosis of colorectal cancer.
2. Cachexia defined by Fearon criteria of weight loss.
3. Signed informed consent.

Exclusion Criteria:

1. Current active reversible causes of decreased food intake.
2. Receiving tube feedings or parenteral nutrition at the time of Screening or Randomization.
3. Have cachexia caused by other reasons.

Conditions4

CRC (Colorectal Cancer)CancerCancer CachexiaColorectal Cancer

Locations1 site

NGM Clinical Study Site
Laredo, Texas, 78041

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