Gustabor Phase 1 - AI-based Creation of a Nutritional Plan to Compensate for Chemotherapy-induced Taste Disorders

Summary

The study investigates taste disorders that commonly occur during or after cancer treatment, often leading to issues such as malnutrition and treatment discontinuation. Although many non-pharmacological recommendations exist, it is unclear which methods are suitable for which individuals. This pilot study aims to use an AI-based, or rule-driven system to generate personalized recommendations based on patients' specific impairments and taste disorder. For the pilot study, the AI will be trained on recipes to create individualized meal plans, helping to identify foods that are likely to be better. The primary endpoint is the assessment of the nutritional intervention as helpful at the second visit within 12 weeks of inclusion.

Eligibility

Inclusion Criteria:

* Age ≥ 18
* Suffering from one of the following tumor entities: Multiple myeloma or malignant tumor of the gastrointestinal tract
* Mainly oral nutrition
* Subjectively perceived tumor therapy-related taste disorder
* At least two clinical presentations planned within 12 weeks with a minimum interval of three weeks
* Ability to participate in nutritional intervention, including use of the online portal and implementation of recipe suggestions (e.g. resources and access to a kitchen), either independently or with third-party support (e.g. by relatives, outpatient care services).

Exclusion Criteria:

* Pregnancy
* Taste disorder explained by other causes (e.g. existing before therapy or COVID disease)
* Placement in an inpatient care facility

Conditions4

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