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A Trial of Varenicline for E-cigarette Cessation

RECRUITINGPhase 2Sponsored by Yale University
Actively Recruiting
PhasePhase 2
SponsorYale University
Started2025-10-14
Est. completion2030-07-30
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations2 sites
View on ClinicalTrials.gov →

NCT07040566

Summary

This is randomized, placebo-controlled clinical trial in treatment-seeking adults who report regular e-cigarette use to test the hypothesis that varenicline is efficacious for quitting e-cigarettes.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* report daily use of an e-cigarette containing nicotine
* live in Connecticut or South Carolina

Exclusion Criteria:

* regular use of other tobacco products besides e-cigarettes
* medical contraindications for varenicline use
* current treatment for tobacco cessation
* lack proficiency in English

Conditions4

CancerE-cigarette UseNicotine DependenceVaping

Locations2 sites

Connecticut

1 site
Yale Cancer Center/Smilow Cancer Hospital at Yale-New Haven
New Haven, Connecticut, 06520

South Carolina

1 site
Hollings Cancer Center at MUSC (HCC)
Charleston, South Carolina, 29425

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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