Tumor-Lymph Node Mapping

Summary

The purpose of this study is to assess the feasibility and safety of ICG-guided intraoperative lymphography for detecting sentinel lymph nodes (SLN) in pediatric patients with solid tumors who require retroperitoneal lymph node dissection/sampling. This trial is a single-site cross-sectional study. The injection of ICG directly into lymphatics draining the primary tumor will take place at the time of operation after the patient is under anesthesia.

Eligibility

Inclusion Criteria:

* Any pediatric patient (under the age of 18 years) being treated at the University of Rochester Medical Center, Department of Surgery.
* Diagnosed with pediatric solid tumor
* Scheduled to undergo lymph node sampling as part of their clinical management.

Exclusion Criteria:

* Subjects with a history of iodide allergies.
* Inability or unwillingness of research participant or parent/legal guardian to give written informed consent.
* Currently pregnant.
* Infants under 650 grams.
* Patients with extensive prior surgery at the primary site or nodal basin expected to affect the lymphatic drainage.

Conditions5

Locations1 site

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