Predicting Outcomes in Posttransplant Diabetes Mellitus Via microRNA

Summary

The study aims to improve the prediction and early detection of post-transplant diabetes mellitus (PTDM) in kidney transplant recipients. The investigators are investigating whether specific microRNA profiles measured 3 months after transplantation can reliably predict the development of PTDM within the following one to two years. Additionally, the investigators are evaluating how traditional risk factors-such as age, immunosuppressive therapy, obesity, and infections like CMV-interact with these microRNA markers. The ultimate goal of this research is to identify early indicators of blood sugar issues, enabling timely interventions to improve health outcomes and personalize patient care after kidney transplantation.

Eligibility

Inclusion Criteria:

* Adult patients undergoing kidney transplantation.
* Absence of pre-existing type 1 or type 2 diabetes mellitus.
* Willingness to provide informed consent and comply with study procedures.

Exclusion Criteria:

* Pre-existing type 1 or type 2 diabetes mellitus.
* Previous organ transplantation.
* Severe comorbidities that could confound the assessment of PTDM (e.g., pancreatic disease).
* Inability to provide informed consent.

Conditions3

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