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The Motor Activity - Subjective Energy (MASE) Project

RECRUITINGN/ASponsored by University of Bern
Actively Recruiting
PhaseN/A
SponsorUniversity of Bern
Started2025-09-02
Est. completion2027-04-30
Eligibility
Age18 Years – 60 Years
Healthy vol.Accepted

Summary

This approach utilizes accelerometry to measure NEA and electronic diaries for real-time psychological assessments, overcoming limitations of traditional methods such as retrospective bias and low ecological validity. Brief episodes of physical activity in daily life, which are distinctly different from structured exercise sessions, are generally linked to improved affective well-being. Notably, feelings of energy are particularly associated with incidental, unstructured, and non-exercise activities. Clinically, psychomotor retardation and diminished mood are key diagnostic features of MDD, with evidence suggesting that lower motor activity differentiates MDD patients from controls and that increased activity correlates with treatment response. In this context, the MASE project aims to design personalized BA interventions that focus on increasing NEA and, in turn, enhancing subjective energy levels to reduce depressive symptoms and prevent relapse.

Eligibility

Age: 18 Years – 60 YearsHealthy volunteers accepted
Inclusion Criteria:

* Sufficient knowledge of the German language
* Written informed consent.
* Score \> 15 on the Montgomery Asberg Depression rating scale (MADRS) for MDD group.
* Remission within the past year and exhibit a MADRS score \< 10 for at least one month for rMDD group

Exclusion Criteria:

* Pregnancy at baseline
* Claustrophobia
* Pacemaker
* Artificial heart valves
* Active implants
* Other psychiatric disorders
* Acute suicidality, change of medication / psychotherapy during the intervention (not dosage but substance).
* For healthy participants: history of any mental health condition or first-degree relative with affective / psychotic disorder

Conditions2

DepressionDepressive Disorder, Major

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