A Study of LY3549492 in Chinese Participants With Type 2 Diabetes Mellitus

Summary

The main purpose of this study is to investigate LY3549492 in Chinese participants with type 2 diabetes. Participation in the study will last about 18 weeks.

Eligibility

Inclusion Criteria:

* Are native Chinese
* Have type 2 diabetes for at least 6 months
* Have been treated with diet and exercise, with or without a stable dose of metformin for at least 3 months
* Have hemoglobin A1c (HbA1c) of at least 7% and no greater than 10%
* Have a body mass index (BMI) of at least 20 milligrams per square meter (kg/m2) and no greater than 40 kg/m2
* Have had a stable body weight for the 3 months prior to screening
* Women must not be of childbearing potential

Exclusion Criteria:

* Have type 1 diabetes or have had an episode of ketoacidosis or hyperosmolar state requiring hospitalization
* Have had an episode of severe hypoglycemia within 6 months or have a history of hypoglycemia unawareness
* Have a clinically significant gastric emptying abnormality
* Have or have a history of pancreatitis
* Have signs and symptoms of liver disease, with the exception of non-alcoholic fatty liver disease
* Have a personal or family history of multiple endocrine neoplasia syndrome type 2 or medullary thyroid carcinoma
* Have an uncontrolled endocrine abnormality
* Have an abnormal blood pressure or pulse rate
* Have a 12-lead electrocardiogram (ECG) abnormality
* Have a significant history within the past 6 months or current evidence of comorbidities capable of altering the absorption, metabolism, or elimination of drugs, or of constituting a risk when taking the study intervention, or of interfering with the interpretation of data

Conditions2

Browse More Trials