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Breast Cancer Screening Adherence for Women at Moderate Risk for Breast Cancer
RECRUITINGSponsored by University of Southern California
Actively Recruiting
SponsorUniversity of Southern California
Started2025-06-02
Est. completion2027-06-02
Eligibility
Age30 Years – 75 Years
SexFEMALE
Healthy vol.Accepted
Locations2 sites
View on ClinicalTrials.gov →
NCT07076147
Summary
This study assesses breast cancer screening adherence for women at moderately increased risk for developing breast cancer based on gene mutation status or empiric risk model estimates. It also seeks to determine facilitators and barriers to screening.
Eligibility
Age: 30 Years – 75 YearsSex: FEMALEHealthy volunteers accepted
Inclusion Criteria:
* \* \>= 30 years
* =\< 75 years
* Women with either:
* Genetic test results showing moderately increased breast cancer risk due to a pathogenic/likely pathogenic variant in ATM, CHEK2, BARD1, RAD51C, or RAD51D (Mutation carrier group) OR
* Calculated lifetime breast cancer risk estimates between 20% and 40% according to the Tyrer-Cuzick V8.0B empiric risk model (Empiric risk group)
* Patients provided breast cancer risk assessments by genetic counselors at USC Norris or LA General Hospital beginning in 2021 and at least 12 months ago
* Women recommended to undergo annual breast MRI and/or annual mammogram beginning at the time of their genetic counseling risk assessment
* English or Spanish speaking patients
Exclusion Criteria:
* \* History of breast cancer before genetic counseling at University of Southern California (USC)
* Any metastatic cancer diagnosis at time of genetic counseling risk assessment
* Deceased
* Patient underwent a risk reducing mastectomy before their genetic counseling risk assessmentConditions3
Breast CancerBreast CarcinomaCancer
Locations2 sites
Los Angeles General Medical Center
Los Angeles, California, 90033
USC / Norris Comprehensive Cancer Center
Los Angeles, California, 90033
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Actively Recruiting
SponsorUniversity of Southern California
Started2025-06-02
Est. completion2027-06-02
Eligibility
Age30 Years – 75 Years
SexFEMALE
Healthy vol.Accepted
Locations2 sites
View on ClinicalTrials.gov →
NCT07076147