Surgical and Obstetric Outcomes in Endometrial Adenocarcinoma and Atypical Endometrial Hyperplasia With Conservative Treatment

Summary

This observational study aims to evaluate the obstetric and oncological outcomes of patients diagnosed with endometrial adenocarcinoma (EAC) or atypical endometrial hyperplasia (AEH) who underwent conservative treatment at the CLASS Hysteroscopy Center of Fondazione Policlinico Universitario A. Gemelli IRCCS in Rome. Eligible patients include women who received hysteroscopic surgery and hormonal therapy either to preserve fertility or due to medical contraindications to standard radical surgery. Follow-up lasts 12 months.

Eligibility

Inclusion Criteria:

* Female patients aged 18 years or older.
* Histological diagnosis of endometrial adenocarcinoma (EAC) or atypical endometrial hyperplasia (AEH).
* Patients who underwent conservative treatment with hysteroscopic resection at the CLASS Hysteroscopy Center, performed by a single experienced surgeon (U.C.).
* Patients treated conservatively due to medical contraindications to radical surgery (e.g., severe comorbidities).
* Signed informed consent for participation in the study.

Exclusion Criteria:

* Patients with other known causes of infertility.
* Patients with non-endometrioid histological subtypes of endometrial adenocarcinoma.
* Patients under 18 years of age.
* Patients who did not provide informed consent for participation.

Conditions5

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