|

Efficacy of Gamma Auditory Stimulation for Cognitive Decline in Older Adults (Study 1)

RECRUITINGN/ASponsored by Chang Gung Memorial Hospital
Actively Recruiting
PhaseN/A
SponsorChang Gung Memorial Hospital
Started2025-11-14
Est. completion2028-09-01
Eligibility
Age60 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07087951

Summary

Animal studies have shown that 40 Hz auditory stimulation alone can improve spatial memory and reduce Aβ deposition. However, human studies using 40 Hz auditory stimulation alone remain limited. Therefore, this study will use a randomized, double-blind, placebo-controlled design to investigate the effects of 40 Hz auditory stimulation on cognitive function, EEG activity, sleep quality, and quality of life in older adults with mild cognitive impairment (MCI) or mild dementia.

Eligibility

Age: 60 Years+Healthy volunteers accepted
Inclusion Criteria:

1. Age over 60 years old.
2. MMSE≤ 24
3. CDR scores of 0.5 and 1
4. Voluntary to sign the Informed Consent Form.

Exclusion Criteria:

1. Diagnosis of other psychiatric or neurological disorders
2. Drug or alcohol addictions.
3. Serious heart, liver or kidney disorders, and visual, auditory or motor impairments interfering with neuropsychological tests.
4. History of clinical stroke, major depressive disorder or dysthymic disorder according to the DSM-5.

Conditions4

Alzheimer's DiseaseAlzheimer's Disease (AD) and Related DisordersCognitive DysfunctionEEG Brain Oscillations

Browse More Trials

Alzheimer's Disease trials

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

This site does not provide medical advice. Always consult your doctor before considering enrollment in a clinical trial. Learn more on our About page.