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Development of Innovative Preclinical Ex Vivo Models for the Study of Sarcomas and Metastases From Solid Tumors

RECRUITINGSponsored by Istituto Ortopedico Rizzoli
Actively Recruiting
SponsorIstituto Ortopedico Rizzoli
Started2024-09-23
Est. completion2031-09-23
Eligibility
Healthy vol.Accepted

Summary

The goal of this observational study is to learn how tumor tissue and blood samples from patients with sarcomas or metastases can be used to create laboratory models that help researchers study cancer behavior and test new treatments. Participants diagnosed with sarcoma or with bone or lung metastases from solid tumors will donate leftover tumor tissue and blood collected during their regular medical care. These samples will be used in the lab to build 3D models of the tumor, test drugs, and identify genetic and molecular markers. No treatments or procedures will be given as part of the study.

Eligibility

Healthy volunteers accepted
Inclusion Criteria:

* Patients (male or female) diagnosed with sarcoma or with bone or lung metastases from solid tumors
* Age between 0 and 85 years
* Availability of sufficient and adequate biological material (tumor tissue and/or blood)
* Signed informed consent for biobanking (BIOTUM)
* Signed informed consent for use of tissue and blood samples in this study

Exclusion Criteria:

* Diagnosis other than sarcoma or metastases from solid tumors
* Missing signed informed consent(s)

Conditions5

Bone Metastases From Solid TumorsBone and Soft Tissue TumorsCancerLung CancerLung Metastases

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