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Memory Deterioration in Alzheimer Disease

RECRUITINGSponsored by Norwegian University of Science and Technology
Actively Recruiting
SponsorNorwegian University of Science and Technology
Started2023-10-15
Est. completion2027-12-31
Eligibility
Age55 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07118137

Summary

Semantic AD

Eligibility

Age: 55 Years+Healthy volunteers accepted
Inclusion Criteria:

* Confirmed diagnosis based on current ICD criteria for AD or MCI .
* \>55years.
* Norwegian native speaker
* Lives at home and not in a health institution

Exclusion Criteria:

* Patients with severe cognitive impairment that prevents assessment with the selected modalities (planned cut-off: CDR \> 2).
* Presence of brain tumors.
* History of traumatic brain injury.
* History of cranial surgery.
* Contraindications to the selected imaging modalities (e.g., 7T MRI or EEG).
* Diagnosis of other neurodegenerative diseases such as Parkinson's disease or ALS.

  7T MRI contraindications:
* Large tattoos close to the head region, permanent makeup or unremoveable piercings
* Certain models of pacemakers (if pacemaker implantet, MRI physicist at 7T-lab will be conferred)
* Implantet metal in body (clips, stents, prothesis, skrews, plates, teeth etc.)

Conditions5

Alzheimer DiseaseAlzheimer's DiseaseMagnetic Resonance ImagingMemory ImpairmentNeurodegenerative Diseases

Interventions2

Blood samplesStool samples

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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