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Home Blood Transfusions

RECRUITINGN/ASponsored by Thomas Jefferson University
Actively Recruiting
PhaseN/A
SponsorThomas Jefferson University
Started2025-06-03
Est. completion2027-06
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site

Summary

This is a pilot single arm study to evaluate the feasibility and acceptability of a home blood transfusion program. Patients will be enrolled with hematologic malignancies and other bone marrow failure syndromes who are transfusion dependent and interested in a home blood transfusion program. Participants enrolled in the study will receive 1-5 units of blood products at home. Data on barriers to administration will be recorded. Surveys and qualitative interviews will be completed to better understand acceptability of the program.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Individuals must meet all of the following inclusion criteria in order to be eligible to participate in the study:
* Provide signed and dated informed consent form Willing to comply with all study procedures and be available for the duration of the study
* Male or female, over the age of 18
* Must meet definition of transfusion dependence (require at least 2 blood product transfusions over a 28-day period)
* Receive their cancer care at SKCCC
* Have a history of blood product transfusions and NO history of transfusion reactions,
* Live within a 30-mile range of the Center City SKCCC location.
* Must be willing to allow people into the home

Exclusion Criteria:

* An individual who meets any of the following criteria will be excluded from participation in this study:
* Patients who have a history of a transfusion reaction
* Heart failure as defined by AHA stage C or NYHA Class II-IV
* Non-English or Spanish speaking
* Are unhoused
* Are incarcerated
* Have poor venous access
* Diagnosis of Solid Tumor malignancy
* Women who are pregnant

Conditions5

Acute Myeloid LeukemiaCancerHematologic MalignancyMyelodysplastic SyndromesTransfusion Dependent Cytopenias

Locations1 site

Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, 19107
Adam Binder, MD215-955-8874adam.binder@jefferson.edu

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