Definitive Radiation Therapy for Inoperable Breast Cancer

Summary

The purpose of this study is to find out if adding radiation therapy to routine medications for breast cancer helps in reducing and preventing the cancer from getting worse. Patients with a locally advanced breast cancer who cannot, or do not want to, undergo surgery are eligible to participate. Participation in this study does not prevent you from undergoing surgery in the future.

Eligibility

Inclusion Criteria:

* Biopsy proven invasive carcinoma of the breast, either lobular, ductal and/or no special type
* T1-T4, N0-2, M0-1 invasive breast carcinoma by radiological or clinical criteria
* Cancer is deemed unresectable, or the patient is a poor surgical candidate as determined following evaluation by a surgeon, or patient declines surgery.
* Life expectancy \> 6 months
* Negative pregnancy test at the time of start of treatment in any female of reproductive age

Exclusion Criteria:

* Concurrent systemic therapy (except for endocrine therapy, HER2-targeted therapy, or immunotherapy which are permitted)
* Prior radiation to ipsilateral breast or regional nodes
* Inability to receive study treatment planning and treatment secondary to body habitus

Conditions3

Locations1 site

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