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Immune Biomarkers in Prostate Cancer Patients Treated With Brachytherapy

RECRUITINGSponsored by University of Erlangen-Nürnberg Medical School
Actively Recruiting
SponsorUniversity of Erlangen-Nürnberg Medical School
Started2025-12
Est. completion2028-07-31
Eligibility
Age18 Years+
SexMALE
Healthy vol.Accepted

Summary

Analysis of peripheral immune cells before, during, and after brachytherapy treatment. Corresponding analysis of tissue samples collected during brachytherapy treatment.

Eligibility

Age: 18 Years+Sex: MALEHealthy volunteers accepted
Inclusion Criteria Arm 1:

* Primary treatment with I-125 seeds or HDR-BT
* No previous treatment for prostate cancer
* Age ≥ 18 years

Inclusion Criteria Arm 2:

* HDR- or PDR-BT
* No radiation therapy within three months before salvage treatment
* Complete documentation available on previous treatment for prostate cancer
* No history of prostatectomy
* Age ≥ 18 years

Exclusion Criteria:

* Pre-existent auto-immune disease
* patients under bloodthinning medication
* substance abuse

Conditions5

CancerProstate Cancer (Diagnosis)Prostate Cancer Patients Treated by RadiotherapyProstate Cancer Patients Who Have Brachytherapy Seed ImplantProstate Cancer Recurrent

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