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No Sedation Versus Daily Interruption of Sedation in Chronic Obstructive Pulmonary Disease Mechanically Ventilated Patients- A Prospective Study

RECRUITINGSponsored by Benha University
Actively Recruiting
SponsorBenha University
Started2024-11-01
Est. completion2025-08-30
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07146698

Summary

this study is to compare no-sedation versus daily interruption of sedation (DIS) in Chronic obstructive pulmonary disease (COPD) patients receiving mechanical ventilation upon the ventilator-free days.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Patients of both sex aged 18 years or older
* The study will include 60 patients divided into 2 equal groups
* Invasive mechanical ventilation
* Patients with COPD patients (post-bronchodilator FEV1/FVC\< 70, and under follow through the department outpatient clinic) exacerbation admitted to the ICU and required invasive mechanical ventilation were recruited.

Exclusion Criteria:

Allergy to sedative which will be used

* renal or hepatic impairment
* proven or suspected psychiatric or neurological impairment
* pregnancy

Conditions3

COPDChronic Obstructive Pulmonary Disease (COPD)Sedation and Analgesia

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