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Identification of New Non-invasive, Predictive, and Diagnostic Biomarkers for Colorectal Cancer

RECRUITINGSponsored by Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Actively Recruiting
SponsorAzienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Started2025-12-01
Est. completion2026-12-01
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07153458

Summary

The study in question is an observational study that aims to identify new non-invasive biomarkers present in the serum of patients with CRC and, subsequently, to create a score capable of predicting the development of CRC. It is an observational study with 3 enrollment arms: Arm 1: Patients undergoing surgery at the U.O.C. of Surgery, with a CRC diagnosis; Arm 2: Subjects with a negative result from the endoscopic examination; Arm 3: Subjects in whom the presence of an adenoma with high-grade dysplasia is found, a condition considered pre-cancerous.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* AIM 1: Patients undergoing surgery at the U.O.C. of Surgery, with a diagnosis of CRC.
* AIM 2: Subjects without colon disease.
* AIM 3: Subjects with adenoma and high-grade dysplasia.

Exclusion Criteria:

* Subject with any other pathology not included in the inclusion criteria.

Conditions3

Adenoma ColonCRC (Colorectal Cancer)Cancer

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