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Triglycerides Glucose Index on Angiographic Profiling of Non-Diabetic Premature Coronary Artery Disease Patients

RECRUITINGSponsored by Sohag University
Actively Recruiting
SponsorSohag University
Started2025-09-04
Est. completion2026-02-01
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07154186

Summary

This study aims to evaluate the impact of the triglyceride-glucose (TyG) index on the angiographic profiling of non-diabetic patients with premature coronary artery disease (CAD).

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Age ≥18 years old.
* Both sexes.
* Non-diabetic patients \[no history of diabetes, hemoglobin A1C (HbA1C) \< 6.5%, fasting glucose \< 126 mg/dL\].
* Confirmed diagnosis of coronary artery disease (CAD) by coronary angiography.

Exclusion Criteria:

* Known diabetes mellitus (type 1 or type 2).
* Previous history of coronary revascularization.
* Severe hepatic or renal dysfunction \[alanine transaminase (ALT)/aspartate aminotransferase (AST) ≥ 5× upper limit of normal (ULN), estimated glomerular filtration rate (eGFR)\< 30 mL/min/1.73 m²\].
* Malignant disease, autoimmune disease, or systemic inflammatory disorders.
* Current use of triglyceride-lowering medications.

Conditions6

Angiographic ProfilingCoronary Artery DiseaseHeart DiseaseNon-DiabeticPrematureTriglycerides Glucose Index

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