7T Brain MRI Scan for Micro-brain Metastasis (microBM) Detection for Patients With Small-cell Lung Cancer (SCLC), Who Decline Prophylactic Cranial Irradiation (PCI)

Summary

Comparison of a 7t MRI to standard of care 1.5t/3t MRI scans to determine if earlier detection of brain metastases are possible on a 7t.

Eligibility

Inclusion Criteria:

* Patient must have a histologically confirmed diagnosis of small-cell lung cancer (SCLC). • Patient must have an MRI of the brain, performed within 4 weeks prior to consent, documenting no evidence of brain metastases or leptomeningeal disease.
* Patient also must not have a history of brain metastases or leptomeningeal disease.
* Patient must refuse PCI and agree to surveillance with brain MRI scans (1.5T/3T).
* Patient must be ≥ 18 years of age.
* Patient must have ECOG Performance Status of 0-2
* Patients must be able to tolerate the 7T MRI

Exclusion Criteria:

* Patient must not have a contraindication to an MRI, such as implanted metal devices or foreign bodies.
* Patient must not have a contraindication to gadolinium contrast administration during MR imaging.
* Patient must not have other metastatic malignancies requiring current active treatment.
* Pregnant patients are excluded. Pregnancy status will be confirmed verbally.

Conditions4

Locations1 site

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